Clinical Trial

Evaluation of Salivary Gal-7, Gal-10 and MMP-9 Levels of Individuals With Different Periodontal Diseases

Recruiting
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Record status
This record was last updated October 28, 2024 (before its estimated January 30, 2025 completion). Its status may not reflect the trial's current state.
Summary
The aim of this study is; detection of Galectin-10, Galectin-7, MMP-9 levels in saliva samples of periodontally healthy, gingivitis and periodontitis patients and the possible correlation between these values and clinical parameters of periodontal diseases. Materials and methods: Samples of saliva were obtained from 60 systemically healthy non-smoker individuals with periodontitis (P, n=20), gingivitis(G, n=20) and healthy periodontium (S, n=20). Full-mouth clinical periodontal measurements including probing depth (PD), clinical attachment level (CAL), bleeding on probing (BOP), gingival index (GI) and plaque index (PI) were also recorded. Enzyme-linked immunosorbent assay (ELISA) was used to determine Galectin-10, Galectin-7 and MMP-9 levels in the biological samples.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2023-12-17; most recent amendment 2024-10-25.
Trial Details
NCT Number NCT06186908
Lead Sponsor Izmir Katip Celebi University
Conditions Periodontal Diseases
Enrollment 60 participants
Start Date 2024-05-02
Primary Completion 2025-01-30 (estimated)
Study Completion 2025-03-24 (estimated)
Updated on ClinicalTrials.gov 2024-10-28