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Evaluation of Salivary Gal-7, Gal-10 and MMP-9 Levels of Individuals With Different Periodontal Diseases

StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated October 28, 2024 (before its estimated January 30, 2025 completion). Its status may not reflect the trial's current state.

Record History

  1. Primary completion date: Nov 30, 2024 to Jan 30, 2025v5
  2. Re-verified, no change to tracked fieldsv4
  3. Start date: Feb 20, 2024 to May 2, 2024
    • Primary completion date: Aug 30, 2024 to Nov 30, 2024
    • Study completion date: Nov 24, 2024 to Mar 24, 2025
    v3
  4. Start date: Sep 22, 2022 to Feb 20, 2024
    • Primary completion date: Mar 30, 2024 to Aug 30, 2024
    v2
  5. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The aim of this study is; detection of Galectin-10, Galectin-7, MMP-9 levels in saliva samples of periodontally healthy, gingivitis and periodontitis patients and the possible correlation between these values and clinical parameters of periodontal diseases. Materials and methods: Samples of saliva were obtained from 60 systemically healthy non-smoker individuals with periodontitis (P, n=20), gingivitis(G, n=20) and healthy periodontium (S, n=20). Full-mouth clinical periodontal measurements including probing depth (PD), clinical attachment level (CAL), bleeding on probing (BOP), gingival index (GI) and plaque index (PI) were also recorded. Enzyme-linked immunosorbent assay (ELISA) was used to determine Galectin-10, Galectin-7 and MMP-9 levels in the biological samples.
Trial Details
NCT Number NCT06186908
Lead Sponsor Izmir Katip Celebi University
Conditions
(from sponsor)		 Periodontal Diseases
Related terms Periodontal Diseases
Enrollment 60 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov