Clinical Trial

Resistance Training to Individuals for Cognitive Impairment With Dementia

Study acronym: TRAIN4BRAIN
Recruiting
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Record status
This record was last updated August 6, 2024 (before its estimated November 30, 2024 completion). Its status may not reflect the trial's current state.
Summary
This research project aims to analyze the effects of different resistance training volumes on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment. First the investigators will analyze the effects of a single resistance training session (acute effects) with one and three sets on hemodynamic and physical performance in individuals with mild cognitive impairment. After, the investigators will analyze the effects of an 8-week resistance training program with one or three sets on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment. The investigators hypothesize that a single resistance training session of one or three sets will increase the acute hemodynamic and physical performance stress in individuals with mild cognitive impairment, although with a higher magnitude in the session with three sets. Furthermore, we hypothesize that eight weeks of resistance training with one or three sets will induce similar improvements in cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2023-12-14; most recent amendment 2024-08-01.
Trial Details
NCT Number NCT06185010
Lead Sponsor University of Beira Interior
Collaborators: Research Center in Sports Sciences, Health Sciences and Human Development
Conditions Mild Cognitive Impairment, Mild Dementia
Enrollment 80 participants
Start Date 2023-12-01
Primary Completion 2024-11-30 (estimated)
Study Completion 2024-12-31 (estimated)
Updated on ClinicalTrials.gov 2024-08-06