Clinical Trial

Comparing SingLe- Vs Multi-Fraction Spine STereotActic Radiosurgery in Spinal Metastases

Recruiting Phase 3
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Summary
The goal of this study is to determine whether fractionated Stereotactic radiosurgery (SRS) for spine metastases is associated with improved local tumor control compared to single-fraction SRS. Patients will be randomized to treatment with spine SRS using either 22 Gy in 1 fraction or 28 Gy in 2 fractions.
Protocol Amendment History 6 amendments
This ClinicalTrials.gov record has been amended 6 times since 2023-12-07; most recent amendment 2026-07-24.
Status change: Not Yet Recruiting → Recruiting 2024-01-05
Trial Details
NCT Number NCT06173401
Lead Sponsor Stanford University
Conditions Spinal Metastases
Enrollment 274 participants
Start Date 2023-12-18
Primary Completion 2028-12 (estimated)
Study Completion 2028-12 (estimated)
Updated on ClinicalTrials.gov 2026-07-27