Clinical Trial

Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients

Recruiting Early Phase 1
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Summary
Arterial hypertension (AH) has been identified as an important public health problem and considered a new epidemic with high mortality and morbidity. High blood pressure (BP) levels increase the chances of coronary artery disease (CAD), heart failure (HF), stroke, chronic renal failure (CRF) and death. Beetroot powder may be an easier way to increase the availability of nitric oxide and consequently vasodilation in these patients. However, studies are needed to evaluate its benefits in patients with AH.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2023-12-05; most recent amendment 2026-04-07.
Trial Details
NCT Number NCT06169241
Lead Sponsor National Institute of Cardiology, Laranjeiras, Brazil
Conditions Arterial Hypertension, Resistant Hypertension, Microvascular Function, Nitrate Supplementation
Enrollment 50 participants
Start Date 2023-11-01
Primary Completion 2026-12 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-04-13