Appropriate Use of Blood Cultures in the Emergency Department Through Machine Learning

The goal of this clinical trial is to study whether the use of our blood culture prediction tool is non-inferior to current practice and if it can improve certain outcomes in all adult patients presenting to the emergency department with a clinical indication for a blood culture analysis (according to the treating physician). The primary endpoint is 30-day mortality. Key secondary outcomes are: * hospital admission rates * in-hospital mortality * hospital length-of-stay. In the intervention group, the physician will follow the advice of our blood culture prediction tool. In the comparison group all patients will undergo a blood culture analysis.

NCT Number	NCT06163781
Lead Sponsor	Amsterdam UMC, location VUmc
Conditions	Artificial Intelligence, Machine Learning, Microbiology, Emergency Service, Hospital, Randomized Controlled Trial
Enrollment	7,584 participants
Start Date	2024-02-19
Primary Completion	2027-01 (estimated)
Study Completion	2027-07 (estimated)
Updated on ClinicalTrials.gov	2024-05-07