Clinical Trial

Pursuing Reduction in Fatigue After COVID-19 Via Exercise and Rehabilitation (PREFACER): A Randomized Feasibility Trial

Study acronym: PREFACER
Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated August 1, 2025 (before its estimated April 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
Long COVID is a complex condition that affects approximately 1.4 million Canadians following SARS-CoV-2 infection. Fatigue is the most common symptom of Long COVID. This feasibility trial will evaluate a new rehabilitation program called COVIDEx for treating fatigue after COVID-19, and compare its effectiveness to the standard treatment currently used. The experimental treatment group will receive an 8-week multi-modal rehabilitation program with two 50-minute sessions per week. 60 participants will be recruited, randomly assigned to the COVIDEx program or standard of care (SoC) and followed for 24 weeks.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2023-11-28; most recent amendment 2025-07-29.
Status change: Not Yet Recruiting → Recruiting 2025-04-08
Trial Details
NCT Number NCT06156176
Lead Sponsor Lawson Research Institute of St. Joseph's
Collaborators: Western University, Canada, Canadian Institutes of Health Research (CIHR)
Conditions Long-COVID, Long COVID-19, Post-COVID-19 Syndrome, Post-COVID Syndrome, Fatigue, Post COVID-19 Condition, Post-COVID Condition
Enrollment 60 participants
Start Date 2025-04-01
Primary Completion 2026-04-01 (estimated)
Study Completion 2026-04-01 (estimated)
Updated on ClinicalTrials.gov 2025-08-01