Clinical Trial

The Effect of Smoking on Peri-implantitis

Active, Not Recruiting
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Summary
the primary aim of this project is to evaluate the microbiological and inflammatory effect of smoking status and smoking severity on periimplantitis lesions. The secondary aim is to compare the effect of smoking on periimplantitis and periodontal microbiota and inflammation in the same individuals. There will include 96 patients, equally divided into four groups: Smokers with peri-implantitis (n=24), non-smoker individuals with peri-implantitis (n=24), smokers with healthy peri-implant tissues (n=24), non-smoker individuals with healthy peri-implant tissues (n=24). Microbiological and biochemical analyses will be performed on the samples taken.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2023-11-20.
Status change: Not Yet Recruiting → Active, Not Recruiting 2025-07-16
Trial Details
NCT Number NCT06150066
Lead Sponsor Mustafa Kemal University
Collaborators: University of Bern, Dokuz Eylul University, Gazi University
Conditions Periimplantitis, Microbial Colonization, Cytokines
Enrollment 96 participants
Start Date 2023-11-21
Primary Completion 2024-07-01 (estimated)
Study Completion 2026-12-21 (estimated)
Updated on ClinicalTrials.gov 2025-07-20