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Safety and Efficacy of Remote Ischemic Conditioning for Patients Taking Off-pump Coronary Artery Bypass Grafting

Study acronym: IMPROVE
StatusRecruiting
PhaseNot applicable
Started
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Record History

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  1. Trial status: Not Yet Recruiting to Recruitingv3 Show 4 more changesShow less
    • Start date changed from estimate of Dec 1, 2024 to Nov 22, 2023
    • Site details revised
    • Collaborators expanded, about 17 words
    • Study title shortened, about 1 word
  2. Start date: Jan 1, 2024 to Dec 1, 2024v2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Remote ischemic conditioning (RIC) is the process of repeated ischemia and reperfusion in the peripheral vessels, which is proved in reducing IRI in vital organs. This IMPROVE trial plans to enroll 648 patients who are diagnosed with coronary artery disease and are going to take off-pump CABG in five centers in China, to access whether RIC can and improve short-term prognosis.
Trial Details
NCT Number NCT06141525
Lead Sponsor First Affiliated Hospital Xi'an Jiaotong University
Collaborators: Beijing Anzhen Hospital, People's Hospital of Qinghai Province, The Second Hospital of Yulin City, Baoji Central Hospital
Conditions
(from sponsor)		 Coronary Artery Bypass Grafting, Remote Ischemic Conditioning, Ischemia-Reperfusion Injury
Related terms Reperfusion Injury
Enrollment 648 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov