Clinical Trial

Preoperative Preradiotherapy TTFields

Study acronym: PORTRAIT
Recruiting
View on ClinicalTrials.gov →
Summary
PreOperative PreRAdIotherapy Tumour Treating Fields (PORTRAIT) is a Phase I study that will test the safety and feasibility of Optune administered preoperatively and preradiotherapy in patients with a new radiological diagnosis of glioblastoma (GBM). Participants will be required to undergo additional MRI sequencing scans and provide blood, tear fluid and tissue samples over a maximum of 6 months. After the study patients will follow their standard treatment pathway.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2023-11-15; most recent amendment 2026-05-05.
Status change: Not Yet Recruiting → Recruiting 2026-05-05
Trial Details
NCT Number NCT06136611
Lead Sponsor The Christie NHS Foundation Trust
Collaborators: University of Manchester, Northern Care Alliance NHS Foundation Trust, NovoCure Ltd.
Conditions Glioblastoma
Enrollment 42 participants
Start Date 2024-12-19
Primary Completion 2026-09-03 (estimated)
Study Completion 2026-12-30 (estimated)
Updated on ClinicalTrials.gov 2026-05-08