Does Sexual Intercourse Affect the Outcomes of Frozen-thawed Embryo Transfer?

The goal of this clinical trial is to test whether sexual intercourse the night after embryo transfer affects thawed embryo implantation rates. Women undergoing one of their first four frozen embryo transfers with a good quality embryo will be randomly assigned to two groups. The study group is subjected to have intercourse without using a condom at the evening/night after the embryo transfer, while the control group will abstain from intercourse for the next 48 hours after the transfer. Researchers will compare the ongoing pregnancy rates between the intervention group and the control group.

NCT Number	NCT06134609
Lead Sponsor	Sheba Medical Center
Conditions	Embryo Transfer, Fertilization in Vitro, Coitus
Enrollment	656 participants
Start Date	2023-11-13
Primary Completion	2026-11 (estimated)
Study Completion	2026-11 (estimated)
Updated on ClinicalTrials.gov	2023-11-18