Robot-assisted ICG-guided Sentinel Node Biopsy in Testicular Cancer

Robot-assisted image-guided sentinel lymph node biopsy (RAISN) in testicular cancer is a novel technique that has not been widely investigated yet. This technique is promising and could be implemented as a future standard in the primary diagnostic work up of clinical stage (CS) I testicular cancer. Current staging strategies have a poor predictive accuracy for occult metastatic disease. So far, feasibility studies used 99mTC-nanocolloid staining and laparoscopy and all patients with tumor-positive nodes received adjuvant systemic treatment. The development of a robot-assisted image-guided lymph node resection technique with indocyanine green (ICG) is potentially more precise, easier to apply and widely available. With this new diagnostic approach the management of newly diagnosed testicular cancer patients might be changed dramatically by reducing overtreatment and treatment-related toxicity with a minimally invasive robot-assisted procedure.

NCT Number	NCT06133543
Lead Sponsor	Heinrich-Heine University, Duesseldorf Collaborators: Intuitive Foundation
Conditions	Germ Cell Tumor, Seminoma, Nonseminomatous Germ Cell Tumor
Enrollment	44 participants
Start Date	2023-09-06
Primary Completion	2026-03-31 (estimated)
Study Completion	2028-03-31 (estimated)
Updated on ClinicalTrials.gov	2025-09-15