Clinical Trial

Endurance Exercise & Virtual Reality for Optimizing Cortical Excitability and Neuroplasticity in PD

Completed
View on ClinicalTrials.gov →
Summary
This study aims to determine the effects of aerobic exercise as a primer to add-on virtual reality (VR)-based rehabilitation on balance, postural control and neuroplasticity (ability of brain to adapt in structure and function) in individuals with Parkinson's disease (PD). This study will utilize two groups - one group will receive the exercise and VR, while the other group will receive stretching exercise and VR over eight weeks. The study team will administer outcomes at baseline, post-intervention (8 weeks) and follow-up (6 weeks after post-assessment).
Protocol Amendment History 3 changes
critical Trial completed 2026-07-31
notable Primary completion moved earlier: 2026-12-31 -> 2025-11-11 2026-07-31
minor Completion moved earlier: 2026-12-31 -> 2025-11-11 2026-07-31
Trial Details
NCT Number NCT06133283
Lead Sponsor The University of Texas Health Science Center at San Antonio
Collaborators: National Center for Advancing Translational Sciences (NCATS)
Conditions Parkinson Disease
Enrollment 16 participants
Start Date 2024-02-09
Primary Completion 2025-11-11 (estimated)
Study Completion 2025-11-11 (estimated)
Updated on ClinicalTrials.gov 2026-07-30