Effects of Rehabilitation Combined With a Maintenance Program Compared to Rehabilitation Alone in Post-COVID-19

Infection with SARS-CoV-2 virus leads to persistent symptoms for more than 12 weeks in 15% of cases ("post-COVID syndrome"). Symptoms like fatigue, dyspnoea, limitations in physical performance and activities, head ache, anxiety symptoms, and depression are heterogenous which limit physical health and participation in daily life activities. In the last years, multidisciplinary rehabilitation programs showed benefits in quality of life and symptom intensity in patients with post-COVID. Therefore, rehabilitation programs are recommended for individuals with Post-COVID by official sites like the German Society of Pulmonology and the European Respiratory Society. Own first data (published at the ERS conference 2023) revealed that one the one hand, inpatient rehabilitation is effective, however, on the other hand, it is challenging to maintain these effects after completing the program. Therefore, the aim of this study is to sustain these benefits by using a digital maintenance program following the rehabilitation program compared to usual care.

NCT Number	NCT06124625
Lead Sponsor	Schön Klinik Berchtesgadener Land Collaborators: Bavarian State Ministry of Health and Care (Funding), Deutsche Rentenversicherung (German pension insurance), Betriebskrankenkassen Landesverband Bayern (Bavarian health insurance) (Design)
Conditions	Post-COVID-19 Syndrome
Enrollment	90 participants
Start Date	2024-01-31
Primary Completion	2025-09-08 (estimated)
Study Completion	2025-09-08 (estimated)
Updated on ClinicalTrials.gov	2026-08-07