Prosthetic Rehabilitation and Its Influence on Masticatory Performance and QoL in Patients Treated for HNC

The main goal of this clinical trial (pilot study) is to evaluate whether prosthetic rehabilitation modifies objective masticatory performance, subjective masticatory performance, quality of life, salivary flow and pH in patients treated for head and neck cancer before and after the placement of fixed and/or removable prostheses. Hypothesis Prosthetic rehabilitation with fixed and/or removable prostheses modifies objective masticatory performance, subjective masticatory performance, quality of life, salivary flow and pH in non-irradiated patients treated for head and neck cancer compared to irradiated patients. Study population The study population will consist of patients treated for head and neck cancer who are candidates for prosthetic rehabilitation. The type of prosthetic treatment recommended will be determined by a dental expert in the treatment of these patients. Interventions 1. \- First session and recruitment: * Oral health status. * Sialometry and salivary pH. * Subjective masticatory performance. * Objective masticatory performance. * Quality of life. 2. \- Prosthodontic treatment. 3. \- Second session (after insertion of the prosthesis) After an adaptation period of ± 15-30 days from the insertion of the prosthesis, the recordings carried out in the first session will be performed again: * Oral health status. * Sialometry and salivary pH. * Subjective masticatory performance. * Objective masticatory performance. * Quality of life. 4. \- Third session (follow-up 6 months) After a period of time of 3 months ± 7 days after the second session, the recordings carried out in the first and second sessions will be performed again: * Oral health status. * Sialometry and salivary pH. * Subjective masticatory performance. * Objective masticatory performance. * Quality of life.

NCT Number	NCT06124222
Lead Sponsor	University of Barcelona
Conditions	Quality of Life, Objective Masticatory Performance, Subjective Masticatory Performance, Oral Health
Enrollment	21 participants
Start Date	2021-11-17
Primary Completion	2025-11 (estimated)
Study Completion	2025-12 (estimated)
Updated on ClinicalTrials.gov	2024-12-05