Sensory and Cognitive Outcomes of Robotic Exercises in Stroke (SCORES)

Based on the findings of meta-analyses, upper limb robotic rehabilitation has shown to enhance daily living activities, motor function, and strength in stroke patients. However, when compared to traditional methods, recent randomized controlled trials conducted on larger participant groups failed to identify significant differences in motor-related outcomes between the two approaches. In addition to motor deficits, stroke survivors often experience cognitive decline and sensory disturbances, which can significantly impede their recovery process. The introduction of multisensory stimulation and an enriched environment through robotic interventions may offer valuable supplementary treatments in these specific areas. Nevertheless, this aspect of treatment has not been thoroughly explored. This study seeks to assess the effectiveness of upper limb robotic rehabilitation in individuals recovering from subacute strokes, in comparison to conventional treatments. Specifically, it aims to determine whether this robotic therapy can lead to improvements in (a) cognitive deficits, (b) somatosensory impairment, and (c) how these sensory and cognitive deficits influence the process of motor recovery.

NCT Number	NCT06109324
Lead Sponsor	Fondazione Don Carlo Gnocchi ETS Collaborators: IRCCS Centro Neurolesi Bonino Pulejo, Scuola Superiore di Studi Universitari e di Perfezionamento Sant'Anna
Conditions	Stroke
Enrollment	126 participants
Start Date	2023-11-13
Primary Completion	2025-05 (estimated)
Study Completion	2026-01 (estimated)
Updated on ClinicalTrials.gov	2024-10-15