Chinese Community Sample of Hierarchical Model of Psychopathology

By validating Hierarchy Model of psychopathology(HiTOP) in Chinese community samples, this study aims for illumating the problem of diagnostic heterogeneity and high comorbidity within existing psychiatric classification systems in Chinese culture. Concurrently, this study also focuses on exploring trans-diagonostic risk and proctective factors underline HiTOP dimensions. the main questions it aims to answer are: 1. Explore HiTOP model cultural differences between western culture and eastern culture. 2. Understand the impact of different dimension of adverse childhood experience on HiTOP structure. 3. Investigate the relationship between individual unique psychological variables and psychopathological dimensions. Participants will receive a detailed survey trying to measure their psychopathology symptoms, adverse childhood experience and psychological variables. This study expects to fallow up participants for 4 years to monitor the symptom changes.

NCT Number	NCT06105970
Lead Sponsor	Shanghai Mental Health Center
Conditions	Mental Health Issue, Adverse Childhood Experience
Enrollment	4,000 participants
Start Date	2023-09-26
Primary Completion	2024-11-01 (estimated)
Study Completion	2027-11-01 (estimated)
Updated on ClinicalTrials.gov	2025-07-10