Clinical Trial

Upper and Lower Extremity Exercise and Exercise-Induced Hypoalgesia in Knee Osteoarthritis

Recruiting
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Record status
This record was last updated December 16, 2024 (before its estimated October 16, 2025 completion). Its status may not reflect the trial's current state.
Summary
The objective of the study is to explore the effects of arm exercise (UE, arm ergometer) vs. leg exercise (LE, cycling ergometer) on exercise-induced hypoalgesia (EIH), central pain mechanisms and knee pain in people with knee osteoarthritis (OA). Furthermore, we will explore relations of socioeconomic status, racial discrimination, acculturative stress, and autonomic function to exercise effects on EIH, central pain mechanisms, and knee pain. This will be a pilot randomized cross-over study where all participants undergo Day 1 (baseline assessments), Day 2 (UE or LE), and Day 3 (UE or LE).
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2023-10-23; most recent amendment 2024-12-10.
Status change: Not Yet Recruiting → Recruiting 2023-11-27
Trial Details
NCT Number NCT06105788
Lead Sponsor University of Texas, El Paso
Conditions Knee Osteoarthritis, Knee Pain Chronic, Central Pain Syndrome
Enrollment 60 participants
Start Date 2023-11-15
Primary Completion 2025-10-16 (estimated)
Study Completion 2025-10-16 (estimated)
Updated on ClinicalTrials.gov 2024-12-16