Fungal Surveillance in Bangladesh

This will be an exploratory descriptive study designed to conduct surveillance for the identification of invasive fungal pathogens among hospitalized patients in Bangladesh at two tertiary care acute-level hospitals. including the Dhaka Medical College Hospital, the Dhaka Hospital of icddr,b, and the National Institute of Cancer Research Hospital (NICRH). Respiratory samples, blood, urine, cerebrospinal fluid, surgical wound infection swabs, and other samples including biopsy tissue specimens will be obtained at intensive care units, general medicine and surgery wards, post-operative care, etc. The collected specimens will be sent to the clinical microbiology laboratories of the surveillance hospitals or to the pathology laboratory (biopsy tissue specimens) to test for Aspergillus, Histoplasms, Candida, Pneumocystis, Cryptococcus, and Mucormycetes. The lab. methods will include microscopy, staining, culture, and biochemical tests mainly and if feasible then some specimens may undergo molecular or immunological methods.

NCT Number	NCT06103331
Lead Sponsor	International Centre for Diarrhoeal Disease Research, Bangladesh Collaborators: Centers for Disease Control and Prevention, Institute of Epidemiology, Disease Control and Research
Conditions	Invasive Fungal Infections
Enrollment	800 participants
Start Date	2022-01-20
Primary Completion	2026-06-01 (estimated)
Study Completion	2026-09-30 (estimated)
Updated on ClinicalTrials.gov	2023-11-22