Autonomic Dysfunction in Functional Dysphonia

The first objective of this research project is to compare the occurrence and frequency of symptoms and/or disorders related to autonomic dysfunction in patients with functional dysphonia with gender- and age-matched vocally healthy controls, using a case-control study. The second objective is to compare the effects of a novel therapy based on autonomic nervous system regulation (i.e., ANS therapy: heart rate variability biofeedback), for functional dysphonia versus coventional voice therapy (CVT) alone or in combination with ANS regulation therapy (i.e., ANS therapy + CVT), using a longitudinal randomized controlled trial (RCT).

NCT Number	NCT06100601
Lead Sponsor	University Ghent Collaborators: Universiteit Antwerpen, University of Utah
Conditions	Functional Voice Disorder, Psychogenic Voice Disorder, Muscle Tension Dysphonia
Enrollment	100 participants
Start Date	2023-10-10
Primary Completion	2026-12 (estimated)
Study Completion	2026-12 (estimated)
Updated on ClinicalTrials.gov	2023-10-25