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Vasopressor Impact on Brain Circulation, Organ Blood Flow and Tissue Oxygenation During Anesthesia

Study acronym: IMPACT
StatusRecruiting
PhasePhase 2/3
Started
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Record History

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  1. Primary completion date: Dec 31, 2026 to Dec 30, 2027
    • Study completion date: Dec 31, 2026 to Dec 31, 2027
    v8
  2. Study description expanded, about 100 wordsv7
  3. Primary and study completion dates: Dec 31, 2025 to Dec 31, 2026v6
  4. Re-verified, no change to tracked fieldsv5
  5. Enrollment target: 40 to 32
    • Study description expanded, about 98 words
    v4
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  1. Trial status: Not Yet Recruiting to Recruiting
    • Start date changed from estimate of Nov 1, 2023 to Dec 20, 2023
    v3
  2. Study description expanded, about 43 wordsv2
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The optimal vasopressor for ensuring organ blood flow and tissue oxygen delivery during surgery remains undetermined. This study aim to compare the effects of noradrenaline vs. phenylephrine infusion on blood flow and oxygen delivery to the brain and various other organs in anesthetized neurosurgical patients.
Trial Details
NCT Number NCT06083948
Lead Sponsor University of Aarhus
Conditions
(from sponsor)		 Hypotension
Related terms Hypotension
Enrollment 32 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov