Clinical Trial

Vasopressor Impact on Brain Circulation, Organ Blood Flow and Tissue Oxygenation During Anesthesia

Study acronym: IMPACT
Recruiting Phase 2/3
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Summary
The optimal vasopressor for ensuring organ blood flow and tissue oxygen delivery during surgery remains undetermined. This study aim to compare the effects of noradrenaline vs. phenylephrine infusion on blood flow and oxygen delivery to the brain and various other organs in anesthetized neurosurgical patients.
Protocol Amendment History 7 amendments
This ClinicalTrials.gov record has been amended 7 times since 2023-10-09; most recent amendment 2026-03-18.
Status change: Not Yet Recruiting → Recruiting 2023-12-19
Trial Details
NCT Number NCT06083948
Lead Sponsor University of Aarhus
Conditions Hypotension
Enrollment 32 participants
Start Date 2023-12-20
Primary Completion 2027-12-30 (estimated)
Study Completion 2027-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-03-19