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Effect of MOPs During Orthodontic Movement in Periodontitis Patients

Study acronym: MOPorthoperi
StatusRecruiting
PhaseNot applicable
Started
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Record status
This record was last updated March 27, 2025 (before its estimated October 2025 completion). Its status may not reflect the trial's current state.

Record History

  1. Site details revisedv3
  2. Start date changed from estimate of Nov 2023 to Dec 15, 2023v2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Micro-osteoperforations (MOPs) cause cortical bone injuries and consequently increase the expression of inflammatory mediators, allowing for increased bone and periodontal ligament remodeling associated with orthodontic movement. It remains unclear the effect of orthodontic intrusion combined with MOPs application on teeth with reduced periodontium. The general objective will be to determine the efficacy of MOPs during orthodontic tooth movement (OTM) in terms of periodontal and orthodontic outcomes in stage IV periodontitis patients, case type 2 with pathological tooth migration (PTM), characterized the presence of at least one flared tooth of the upper-anterior sextant with an intrabony defect (intrabony component \<5mm)
Trial Details
NCT Number NCT06068270
Lead Sponsor Universidad Complutense de Madrid
Conditions
(from sponsor)		 Stage IV Periodontitis, Orthodontic Tooth Movement
Related terms Periodontitis
Enrollment 28 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov