Cardiac Biomarkers for the Quantification of Myocardial Damage After Cardiac Surgery

The aim of the study is to clarify whether the perioperative release of the cardiac biomarkers troponin I, troponin T and CK-MB consistently correlate with visualizable myocardial damage, and to what extent these biomarkers are comparable by means of their kinetics and dynamics. Due to the uncertainty regarding the validity of cardiac biomarkers in the diagnosis of myocardial infarction, the answer to these questions could have a considerable influence on internationally valid guidelines and definitions. International studies, especially in the field of coronary surgery and coronary artery disease treatment refer to these definitions, in particular, the adequate treatment of affected patients is directly dependent on them.

NCT Number	NCT06066970
Lead Sponsor	Jena University Hospital
Conditions	Cardiac Valve Disease
Enrollment	100 participants
Start Date	2023-09-05
Primary Completion	2025-09 (estimated)
Study Completion	2025-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-09-26