Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT06062550 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Different Dose Esketamine and Dexmedetomidine Combination for Supplemental Analgesia After Scoliosis Correction Surgery

StatusActive, Not Recruiting
PhasePhase 4
Started
View on ClinicalTrials.gov ↗

Record History

See every version on ClinicalTrials.gov ↗

  1. Trial status: Recruiting to Active, Not Recruiting
    • Primary completion date changed from estimate of Sep 2025 to Oct 23, 2025
    • Study completion date: Oct 2025 to Oct 2026
    • Site details revised
    v5
  2. Trial status: Not Yet Recruiting to Recruitingv4 Show 4 more changesShow less
    • Primary completion date: Dec 2025 to Sep 2025
    • Study completion date: Dec 2026 to Oct 2025
    • Start date changed from estimate of Oct 2023 to Oct 24, 2023
    • Site details revised
  3. Secondary endpoints: details revised at 1 of 8 entriesv3
  4. Secondary endpoints: details revised at 1 of 8 entries
    • Study description revised
    v2
  5. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Scoliosis correction surgery is associated with severe pain. Patients after scoliosis correction surgery usually require high dose opioids and long duration analgesia, which may increase side effects and drug tolerance. In a recent trial, mini-dose esketamine and dexmedetomidine combination as a supplement to sufentanil significantly improved analgesia and subjective sleep quality after spinal correction surgery without increasing adverse events; however, the proportion of patients with moderate-to-severe pain remained high. The authors speculate that increasing esketamine dose in the combination may further improve analgesic effects.
Trial Details
NCT Number NCT06062550
Lead Sponsor Peking University First Hospital
Conditions
(from sponsor)		 Scoliosis Correction, Esketamine, Dexmedetomidine, Postoperative Analgesia, Chronic Postsurgical Pain
Related terms Postoperative Pain
Enrollment 312 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov