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Induced Hypertension in Acute PRogrESsive Perforating Artery Stroke Using Peripheral Dilute noREpinephrine

Study acronym: PRESSURE
StatusRecruiting
PhasePhase 3
Started2024-11-28
View on ClinicalTrials.gov ↗

Amendment history

2025-01-07
notable
Not Yet Recruiting→Recruiting Study Status, Contacts/Locations v1
Trial statusNot Yet Recruiting→Recruiting
Primary completion date2025-10-01→2027-08-28
Completion date2025-12-01→2027-11-28
Start dateestimated 2024-01-01→confirmed 2024-11-28
Study sites0→1
2023-09-22
minor
Original filing
PRESSURE is a multicenter, prospective, randomized, open, blinded end-point assessed (PROBE) trial, that aims to evaluate the efficacy and safety of drug-induced hypertension using peripheral dilute norepinephrine, in patients with acute ischemic stroke in a perforating artery territory and experiencing early neurological deterioration.
Trial Details
NCT Number NCT06059144
Lead Sponsor University Hospital, Bordeaux
Conditions Stroke, Acute, Stroke, Ischemic
Enrollment 358 participants
Start Date 2024-11-28
Primary Completion 2027-08-28 (estimated)
Study Completion 2027-11-28 (estimated)
Updated on ClinicalTrials.gov 2025-01-09