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L-arginine for Knee Osteoarthritis Patients

StatusRecruiting
PhaseNot applicable
Started
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Record status
This record was last updated June 2, 2025 (before its estimated September 30, 2025 completion). Its status may not reflect the trial's current state.

Record History

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  1. Primary completion date: Dec 30, 2024 to Sep 30, 2025v4 Show 4 more changesShow less
    • Enrollment target: 230 to 340
    • Study completion date: Mar 31, 2025 to Sep 30, 2025
    • Secondary endpoints revised (14)
    • Collaborators: 4 to 3
  2. Trial status: Not Yet Recruiting to Recruiting
    • Study sites: 0 to 1
    • Start date changed from estimate of Mar 1, 2024 to Mar 20, 2024
    v3
  3. Enrollment target: 100 to 230v2 Show 5 more changesShow less
    • Start date: Oct 1, 2023 to Mar 1, 2024
    • Primary endpoint revised
    • Primary completion date: Oct 30, 2024 to Dec 30, 2024
    • Study completion date: Jan 31, 2025 to Mar 31, 2025
    • Secondary endpoints: 15 to 14
  4. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study will examine the pain-relief efficacy and safety of L-arginine in knee OA patients.
Trial Details
NCT Number NCT06054633
Lead Sponsor Xiangya Hospital of Central South University
Collaborators: Massachusetts General Hospital, School of Medicine, University of Nottingham, Memorial University of Newfoundland
Conditions
(from sponsor)		 Osteoarthritis, Knee
Related terms Osteoarthritis, Osteoarthritis, Knee, Pain
Enrollment 340 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov