Clinical Trial

Non-Invasive Brain Stimulation and Cognitive Training for Depressive Symptomatology Related to Breast Cancer (ONCODEP)

Study acronym: ONCODEP
Active, Not Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated July 20, 2025 (before its estimated September 2025 completion). Its status may not reflect the trial's current state.
Summary
The goal of this clinical trial is to test a home-delivered intervention that combines Non-Invasive Brain Stimulation techniques (transcranial direct and alternating current stimulation -tDCS and tACS-) and Online Cognitive Training (OCT) to treat depressive symptomatology and cognitive decline associated with breast cancer. The main questions aims to be answered are: * To analyze the efficacy and feasibility of the intervention to treat depressive symptomatology. * To analyze the efficacy and feasibility of the intervention to treat cognitive decline. * To evaluate the medium and long-term effects (1, 3 and 6 months) of intervention. An OCT program and a portable wireless tDCS/tACS system will be used to perform the intervention at home. Patients will be divided into four treatment groups, depending on whether they will receive the OCT applied independently or combined with tDCS/tACS active or sham. In addition, saliva samples will be collected to identify bomarkers predictive of treatment efficacy.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2023-09-18; most recent amendment 2025-07-16.
Status change: Recruiting → Active, Not Recruiting 2025-07-16
Status change: Not Yet Recruiting → Recruiting 2023-11-28
Trial Details
NCT Number NCT06053775
Lead Sponsor University of Santiago de Compostela
Collaborators: Fundacin Biomedica Galicia Sur
Conditions Depressive Symptoms, Cognitive Impairment
Enrollment 82 participants
Start Date 2023-09-27
Primary Completion 2025-09 (estimated)
Study Completion 2025-09 (estimated)
Updated on ClinicalTrials.gov 2025-07-20