The Scottish Aortic Stenosis LongiTudinal Imaging and biomarkeR (SALTIRE) Programme

The goal of this observational study is to understand the processes of what causes and accelerates the disease progress in aortic stenosis and following aortic valve replacement. Participants will undergo transthoracic echocardiography every 6 months, with annual visits for state-of-the-art scanning techniques including positron-emission tomography combined with computed tomography or magnetic resonance imaging with radiotracers designed to look at disease processes including fibrosis, calcification, inflammation and thrombosis activity.

NCT Number	NCT06047561
Lead Sponsor	University of Edinburgh
Conditions	Aortic Stenosis
Enrollment	300 participants
Start Date	2023-05-22
Primary Completion	2028-05-22 (estimated)
Study Completion	2028-05-22 (estimated)
Updated on ClinicalTrials.gov	2025-09-17