Clinical Trial

Oral Care With 3% Hydrogen Peroxide (Oroxid®) in ICU - Effects on the Lower Airway Microbial Colonisation

Study acronym: HyperMICROBE
Unknown Phase 4
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Record status
This record was last updated July 26, 2024 (before its estimated June 2025 completion). Its status may not reflect the trial's current state.
Summary
HyPerMICROBE is a single-centre, controlled, randomised, prospective, superiority clinical trial to compare the efficacy of daily oral care with 3% hydrogen peroxide (Oroxid®) versus standard of care (0.2% chlorhexidine digluconate) on the cumulative incidence of lower respiratory tract microbial colonisation in mechanically ventilated adult critically ill patients.
Protocol Amendment History 1 change
critical Trial status changed: Recruiting → Unknown 2026-08-02
Trial Details
NCT Number NCT06045429
Lead Sponsor Charles University, Czech Republic
Conditions VAP - Ventilator Associated Pneumonia
Enrollment 160 participants
Start Date 2024-05-01
Primary Completion 2025-06 (estimated)
Study Completion 2025-12 (estimated)
Updated on ClinicalTrials.gov 2024-07-26