Timing of Endoscopy in Cirrhotic Patients with Acute Variceal Bleeding

Endoscopy is important for the diagnosis and treatment of acute upper gastrointestinal bleeding (AUGIB), especially acute variceal bleeding (AVB), in patients with liver cirrhosis. However, the optimal timing of endoscopy remains controversial, primarily because the currently available evidence is of poor quality, and the definition of early endoscopy is also very heterogeneous among studies. Herein, a multicenter randomized controlled trial (RCT) is performed to explore the impact of timing of endoscopy on the outcomes of cirrhotic patients with AVB.

NCT Number	NCT06031402
Lead Sponsor	General Hospital of Shenyang Military Region
Conditions	Acute Upper Gastrointestinal Bleeding, Acute Variceal Bleeding
Enrollment	368 participants
Start Date	2024-09-04
Primary Completion	2026-12 (estimated)
Study Completion	2026-12 (estimated)
Updated on ClinicalTrials.gov	2025-02-27