Clinical Trial

The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults

Study acronym: Mito-Frail
Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial is to test the effects of MitoQ supplementation in older adults and frail older adults with physical dysfunction and/or cognitive dysfunction. The main question\[s\] it aims to answer are: * To compare vascular function, oxidative stress levels, and physical and cognitive function among older adults and frail older adults with physical and cognitive dysfunction * To determine whether MitoQ supplementation has the potential to improve vascular function in central and cerebral vessels * To determine whether MitoQ supplementation can enhance physical and cognitive capabilities.
Protocol Amendment History 7 amendments
This ClinicalTrials.gov record has been amended 7 times since 2023-08-30; most recent amendment 2026-01-08.
Status change: Not Yet Recruiting → Recruiting 2024-10-16
Status change: Recruiting → Not Yet Recruiting 2024-02-08
Status change: Not Yet Recruiting → Recruiting 2024-02-08
Trial Details
NCT Number NCT06027554
Lead Sponsor UConn Health
Collaborators: National Institute on Aging (NIA), University of Connecticut
Conditions Frailty, Mild Cognitive Impairment, Aging
Enrollment 60 participants
Start Date 2024-10-07
Primary Completion 2027-03-01 (estimated)
Study Completion 2028-02-01 (estimated)
Updated on ClinicalTrials.gov 2026-08-12