Clinical Trial

A Novel Therapy With a 1-Month Ultrashort Regimen to Halt Progression From Latent Infection to Active Tuberculosis Among Close Contacts (The TB-YOUTH Study)

Study acronym: TB-YOUTH
Recruiting Phase 3
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Summary
This is a prospective, multi-center, open-label, cluster randomized controlled clinical trial conducted in school settings to estimate the non-inferiority effect of 1H3P3 compared with 3HR.
Protocol Amendment History 7 amendments
This ClinicalTrials.gov record has been amended 7 times since 2023-08-28; most recent amendment 2026-07-13.
Status change: Not Yet Recruiting → Recruiting 2023-09-13
Trial Details
NCT Number NCT06022146
Lead Sponsor Huashan Hospital
Conditions Tuberculosis, Latent Tuberculosis
Enrollment 3,520 participants
Start Date 2023-09-01
Primary Completion 2026-09-01 (estimated)
Study Completion 2026-09-01 (estimated)
Updated on ClinicalTrials.gov 2026-07-14