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Senolytics to Improve Osteoporosis Therapy

Study acronym: SENIOR
StatusActive, Not Recruiting
PhasePhase 2
Started
View on ClinicalTrials.gov ↗

Record History

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  1. Re-verified, no change to tracked fieldsv5
  2. Trial status: Recruiting to Active, Not Recruitingv4 Show 4 more changesShow less
    • Primary and study completion dates: Dec 31, 2025 to Apr 30, 2026
    • Eligibility criteria shortened, about 15 words
    • Study description revised
    • Site details revised
  3. Collaborators revised (2)v3
  4. Start date changed from estimate of Sep 1, 2023 to Sep 6, 2023v2
  5. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This randomised clinical trial aims to study osteoporosis as a disease of accelerated skeletal aging caused by the accumulation of senescent cells within the skeleton and investigate the effects and safety of senolytics and antioxidant therapy on bone.
Trial Details
NCT Number NCT06018467
Lead Sponsor Odense University Hospital
Collaborators: Odense Patient Data Explorative Network, The Novo Nordisk Foundation Center for Basic Metabolic Research
Conditions
(from sponsor)		 Osteopenia, Osteoporosis, Age-related Bone Loss
Related terms Bone Diseases, Metabolic, Osteoporosis
Enrollment 120 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov