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A Phase II Study Evaluating JAB-21822 Monotherapy in Adult Patients With Pancreatic Cancer and Other Solid Tumors Harboring the KRAS p.G12C Mutation.

StatusRecruiting
PhasePhase 2
Started
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Record History

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  1. Minor Re-verified, no change to tracked fieldsv7
  2. Notable Primary completion date: May 2025 to Dec 31, 2026
    • Study completion date: Nov 2025 to Dec 31, 2027
    v6
  3. Minor Study Identification, Study Status, Contacts/Locationsv5
  4. Notable Lead sponsor: Jacobio Pharmaceuticals Co., Ltd. to Allist Pharmaceuticals, Inc.v4 Show 5 more changesShow less
    • Enrollment target: 69 to 88
    • Eligibility criteria expanded, about 38 words
    • Secondary endpoints revised (7)
    • Study description expanded, about 63 words
    • Study title expanded, about 10 words
  5. Minor Study sites: 30 to 31
    • Eligibility criteria shortened, about 37 words
    v3
  6. Notable Trial status: Not Yet Recruiting to Recruiting
    • Study sites: 2 to 30
    • Start date changed from estimate of Nov 2023 to Oct 27, 2023
    v2
  7. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Patients with other advanced solid tumors (excluding NSCLC and CRC) who have progressed after prior systemic therapy or are intolerant and lack satisfactory alternative treatment options, aiming to evaluate the efficacy and safety of Glecirasib in these patients.
Trial Details
NCT Number NCT06008288
Lead Sponsor Allist Pharmaceuticals, Inc.
Conditions
(from sponsor)
KRAS P.G12C, Pancreatic Cancer, Solid Tumor
Related terms Pancreatic Neoplasms
Enrollment 88 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov