Validation of the Performance of the French Version of the Cerebellar Cognitive-Affective Syndrome Scale (CCASS) as a Screening Test for Cerebellar Cognitive-affective Syndrome: a National Multicenter Study

The primary objective of the study is to assess the performance of the French version of the Cerebellar Cognitive-Affective Syndrome Scale (CCASS) as a screening test for cerebellar cognitive-affective syndrome. The primary endpoint will be the sensitivity of version 1A of the French scale. The result will be considered positive if the patient fails at least one of the scale's subtests. The diagnosis of a cerebellar cognitive-affective syndrome will be made on the basis of a pathological score in the executive, language, visuospatial or psychoaffective domains of the neuropsychological evaluation (gold standard).

NCT Number	NCT06005844
Lead Sponsor	Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Conditions	Cerebellar Cognitive-affective Syndrome
Enrollment	217 participants
Start Date	2023-11-09
Primary Completion	2026-10 (estimated)
Study Completion	2027-03 (estimated)
Updated on ClinicalTrials.gov	2025-05-16