Oral, Chemosensory and Trigeminal Functions in Allo-HSCT

The goal of this prospective, cohort study is to learn about smell, taste and trigeminal dysfunction in patients receiving allogeneic hematopoietic stem cell transplantation (allo-HSCT). The research team hypothesizes that treatment with allo-HSCT will induce: * Distortion of taste and smell and trigeminal functions like cooling, tingling, and burning sensations. * Reduced saliva production leading to oral dryness and dental caries. * Changes in the connectivity of the taste-, smell- and pain-cortical brain regions.

NCT Number	NCT06003660
Lead Sponsor	University of Oslo
Conditions	Hematopoietic Stem Cell Transplantation
Enrollment	70 participants
Start Date	2023-08-10
Primary Completion	2026-12-30 (estimated)
Study Completion	2028-03-01 (estimated)
Updated on ClinicalTrials.gov	2026-05-01