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NCT06003036 · ClinicalTrials.gov record · last posted 2026-08-10

Accelerated Transcranial Magnetic Stimulation for People With Schizophrenia Treated With Clozapine

StatusCompleted
PhaseNot applicable
Started2023-12-01
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from the ClinicalTrials.gov record
In this study, the investigators will examine whether a type of repetitive transcranial magnetic stimulation called accelerated intermittent theta burst stimulation (iTBS) can augment neurocognition in individuals who receive treatment with clozapine. Following a baseline evaluation and magnetic resonance imaging (MRI), participants will undergo a session of iTBS +MRI and session of sham delivery + MRI. The order for these sessions will be blinded and randomized. The investigators predict that accelerated iTBS will enhance neurocognition relative to sham delivery.

Protocol amendment history 3 changes detected by DataLookout

2026-08-11
Trial completed
2026-08-11
Primary completion moved earlier: 2026-02-28 → 2026-01-12
2026-08-11
Completion moved earlier: 2026-07 → 2026-01-12
Trial Details
NCT Number NCT06003036
Lead Sponsor Deepak K. Sarpal, M.D.
Collaborators: National Institute of Mental Health (NIMH)
Conditions Schizophrenia, Schizoaffective Disorder
Enrollment 30 participants
Start Date 2023-12-01
Primary Completion 2026-01-12 (estimated)
Study Completion 2026-01-12 (estimated)
Updated on ClinicalTrials.gov 2026-08-10