Clinical Trial

Neoadjuvant Radiotherapy and Immediate Implant-Based Breast Reconstruction

Recruiting
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Record status
This record was last updated March 17, 2025 (before its estimated July 8, 2025 completion). Its status may not reflect the trial's current state.
Summary
Neoadjuvant radiotherapy(NART) followed by mastectomy and immediate DIEP flap reconstruction is feasible and technically safe. However, reports of NACT followed immediate implant-based breast reconstruction are rare. Some studies have shown that NART followed immediate implant-based breast reconstruction seems feasible and can be safely attempted. It's well known that radiotherapy after implant-based breast reconstruction have negative effects on implant and cosmetic results. So, investigators conducted a polit study to learn about acute post-surgical complications following skin-sparing mastectomy and immediate implant-based breast reconstruction after NART.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2023-08-08.
Trial Details
NCT Number NCT05992870
Lead Sponsor Hubei Cancer Hospital
Conditions Breast Cancer, Implant Breast Reconstruction, Neoadjuvant Radiotherapy
Enrollment 40 participants
Start Date 2023-07-08
Primary Completion 2025-07-08 (estimated)
Study Completion 2025-10-31 (estimated)
Updated on ClinicalTrials.gov 2025-03-17