Clinical Trial

Electroencephalographic Biomarker to Predict Postoperative Delirium

Active, Not Recruiting
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Summary
Acute post-operatory cognitive dysfunction states are one of the most important complications in older patients that underwent surgery. Among them postoperative delirium (POD) is the the most studied. Patients who develop delirium have poorer long-term outcomes, such as longer length of hospital stay, institutionalization at discharge, and even higher mortality, and consequently, the human and economic costs significantly increase for the health system. Here the research team will use an observational cohort, investigator blinded in five-center with a primary endpoint to validate intraoperative EEG analysis as a reliable biomarker of postoperative delirium.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2023-08-07; most recent amendment 2025-11-17.
Status change: Recruiting → Active, Not Recruiting 2025-11-17
Status change: Not Yet Recruiting → Recruiting 2023-12-06
Trial Details
NCT Number NCT05992506
Lead Sponsor University of Chile
Collaborators: Instituto Nacional del Cancer, Chile, Pontificia Universidad Catolica de Chile, Hospital Base San Jose Osorno, Clinica Santa Maria
Conditions Postoperative Delirium
Enrollment 264 participants
Start Date 2023-09-01
Primary Completion 2025-10-31 (estimated)
Study Completion 2026-06-30 (estimated)
Updated on ClinicalTrials.gov 2025-11-20