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Cue Effects in Human Addiction: Pavlovian to Instrumental Transfer

Study acronym: ReCoDe
StatusUnknown
PhaseNot specified
Started2020-11-24
View on ClinicalTrials.gov ↗
Record status
This record was last updated August 21, 2024 (before its estimated December 31, 2024 completion). Its status may not reflect the trial's current state.

Amendment history

2026-09-06
Trial status changed: Recruiting → Unknown
2024-08-20
Study Status v1
Trial statusRecruiting→Unknown
Primary completion date2023-12-31→2024-12-31
Completion date2023-12-31→2024-12-31
2023-08-07
Original filing
Individuals with substance use disorders (SUD) have to cope with drug-related cues and contexts, which can affect instrumental drug seeking as shown with Pavlovian to instrumental transfer (PIT) paradigms in animals and humans. The investigators aimed to investigate the impact of acute and chronic stress on Pavlovian-to-instrumental transfer (PIT), how PIT it is associated with cognitive control abilities and whether such effects predict losing vs. regaining control in subjects with AUD. Moreover, the investigators aimed to develop a novel full transfer task that assesses both, general and specific PIT to investigate whether specific PIT differs between alcohol use disorder (AUD) and control subjects.
Trial Details
NCT Number NCT05992272
Lead Sponsor Charite University, Berlin, Germany
Collaborators: Technische Universität Dresden
Conditions Alcohol Use Disorder (AUD), Alcoholism, Substance Use Disorders, Smoking, Tobacco, Stress Reaction, Stress
Enrollment 300 participants
Start Date 2020-11-24
Primary Completion 2024-12-31 (estimated)
Study Completion 2024-12-31 (estimated)
Updated on ClinicalTrials.gov 2024-08-21