Clinical Trial

Sevoflurane General Anesthetic and Spatial Memory in Humans

Recruiting
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Record status
This record was last updated November 20, 2025 (before its estimated November 30, 2025 completion). Its status may not reflect the trial's current state.
Summary
The goal of this observational study is to learn about the effect of general anesthetic on spatial memory in adults who will undergo to an elective surgery. The main question it aims to answer is: • A surgical event under general anesthesia with sevoflurane transiently impairs spatial memory in humans and induces an increase in inflammatory cytokines. Participants will perform a virtual maze test and plasma samples will be taken before and after surgery.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2023-08-07; most recent amendment 2025-11-17.
Status change: Not Yet Recruiting → Recruiting 2023-12-06
Trial Details
NCT Number NCT05991817
Lead Sponsor University of Chile
Conditions Spatial Memory Disorder
Enrollment 22 participants
Start Date 2023-08-14
Primary Completion 2025-11-30 (estimated)
Study Completion 2025-12-30 (estimated)
Updated on ClinicalTrials.gov 2025-11-20