Extreme Morphology and Metabolic Health

Researchers at the University of Bath are investigating the metabolism of individuals with extreme body size, including those with skeletal dysplasia (commonly known as dwarfism), to manage health risks such as heart disease. By better understanding how body size could change how the body processes food, or how being bigger or smaller may influence eating habits, healthy living guidelines to tackle issues such as obesity and overweight in these populations can be improved. With help from expertise in the psychology field, this research will also investigate whether the mental health of these individuals has been affected by their size. On the whole, this study will involve one 24-hour visit to a research laboratory at the University of Bath, followed by a 2-week monitoring period to capture 'normal' physical activity and eating routines.

NCT Number	NCT05991609
Lead Sponsor	University of Bath Collaborators: University of Bristol
Conditions	Skeletal Dysplasia
Enrollment	102 participants
Start Date	2023-06-17
Primary Completion	2025-09-30 (estimated)
Study Completion	2035-09-28 (estimated)
Updated on ClinicalTrials.gov	2025-02-10