Clinical Trial

Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies

Recruiting Phase 2/3
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Record status
This record was last updated June 18, 2025 (before its estimated September 29, 2025 completion). Its status may not reflect the trial's current state.
Summary
The goal of this clinical trial is to compare the outcomes of High-volume saline irrigation vs Povidone-iodine solution cleaning of the intraoperative incision wound in preventing superficial surgical site infections in patients undergoing emergency laparotomies. The main question it aims to answer are: * Incidence of SSI after intervention * Length of hospital stay Participants will be randomly assigned to two groups receiving either of the two groups: Group A: 1000ml of IOWI with saline solution prior to incision closure Group B: The incisional wound will be closed conventionally without irrigation. Researchers will compare groups A( experimental group) and B (control group) to compare the incidence of superficial surgical site infections after intervention.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2023-08-09; most recent amendment 2025-06-14.
Trial Details
NCT Number NCT05989386
Lead Sponsor Dow University of Health Sciences
Conditions Surgical Site Infection, Surgical Wound, Surgical Incision, Emergency Laparotomies, Laparotomies, Post Operative Wound Infection, Wound Infection, Seroma
Enrollment 200 participants
Start Date 2023-04-29
Primary Completion 2025-09-29 (estimated)
Study Completion 2025-12-29 (estimated)
Updated on ClinicalTrials.gov 2025-06-18