Psychoeducational Intervention for Families With a Member Affected by Major Depression

Major depressive disorder (MDD) is the most common mental disorder. It can be a huge burden not only for the person affected by it, but also for his/her whole family. The goal of this clinical trial is to test the efficacy of a family supportive intervention called psychoeducational family intervention (PFI) compared to a brief informative intervention in families with a member affected by MDD. Families will participate in one of the two interventions for a period of 6 months more or less, and they will be asked to answer some questionnaires about how much MDD impacts on their everyday life and the patient's symptoms, in order to understand whether a more structured intervention such as PFI can be useful for families in order to better deal with this complicated illness.

NCT Number	NCT05988333
Lead Sponsor	University of Campania Luigi Vanvitelli Collaborators: Università degli Studi di Brescia, University of Bologna, University of Catanzaro, Università degli Studi 'G. d'Annunzio' Chieti e Pescara, University of Cagliari, University of Florence, Università degli Studi di Ferrara, University of Foggia, Universita degli Studi di Genova, University of Milan, University of Modena and Reggio Emilia, Università degli Studi del Piemonte Orientale Amedeo Avogadro, University of Parma, University Of Perugia, University of Pisa, Università Politecnica delle Marche, University of Roma La Sapienza, University of Rome Tor Vergata, Catholic University of the Sacred Heart, Università degli Studi di Sassari, University of Siena, Università degli studi di Trieste, Universita di Verona
Conditions	Depressive Disorder, Major
Enrollment	384 participants
Start Date	2023-09-27
Primary Completion	2026-09 (estimated)
Study Completion	2026-09 (estimated)
Updated on ClinicalTrials.gov	2024-04-19