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NCT05987345 · ClinicalTrials.gov record · last posted 2024-07-22

Trial of Pulsed Electric Field Therapy in Patients With Late-stage Non-small Cell Lung Cancer

StatusUnknown
PhaseNot applicable
Started2023-07-06
View on ClinicalTrials.gov ↗
Record status
This record was last updated July 22, 2024 (before its estimated July 31, 2024 completion). Its status may not reflect the trial's current state.
from the ClinicalTrials.gov record
The goal of this clinical trial is to verify the safety and clinical benefit of pulsed electric field(PEF) treatment of metastatic non-small cell lung cancer(NSCLC) patients with acquired resistance to anti programmed cell death protein 1(PD-1) monoclonal antibody therapy. The main questions it aims to answer are: * Safety of PEF treatment of metastatic NSCLC patients. * Control of ablated and other targeted lesions. * Local and peripheral immunoregulation effect. PEF energy will be delivered to preselected lesions of participants, then anti PD-1 will be routinely administrated if no adverse event(AE)/serious adverse event(SAE) which need medical intervention occurs.

Protocol amendment history 1 change detected by DataLookout

2026-08-02
Trial status changed: Recruiting → Unknown
Trial Details
NCT Number NCT05987345
Lead Sponsor Energenx Medical LTD.
Conditions NSCLC
Enrollment 10 participants
Start Date 2023-07-06
Primary Completion 2024-07-31 (estimated)
Study Completion 2024-07-31 (estimated)
Updated on ClinicalTrials.gov 2024-07-22