National Blood Pressure Screening in Children to Improve Paediatric Healthcare in South Africa

The Childhood Hypertension Consortium of South Africa (CHCSA) was established to foster relationships between the healthcare sector and schools through community engagement and outreach as well as contributing to the decolonization of normative paediatric blood pressure reference values. To date, there has been no nation-wide project in South Africa to determine nationally representative normal blood pressure reference values, nor to estimate the true prevalence of hypertension in the paediatric population of the country. This study will provide critical information on the understanding of blood pressure and hypertension in children, especially of African ancestry. Not only will this effort contribute to the development of the first nationally representative normal reference values of blood pressure but will also benefit healthcare providers in the sector with a clear guideline on the management of high blood pressure in children as developed by experts working with these challenges daily.

NCT Number	NCT05982847
Lead Sponsor	North-West University, South Africa Collaborators: Medical Research Council, South Africa, University of Cape Town, University of Limpopo, Walter Sisulu University, University of KwaZulu, Red Cross War Memorial Childrens Hospital, University of Witwatersrand, South Africa, University of Zurich, Groote Schuur Hospital, Nelson Mandela Metropolitan University, Chris Hani Baragwanath Academic Hospital, University of the Free State
Conditions	Hypertension, Obesity, Adolescent, Obesity, Childhood
Enrollment	22,464 participants
Start Date	2024-04-01
Primary Completion	2028-11-30 (estimated)
Study Completion	2028-11-30 (estimated)
Updated on ClinicalTrials.gov	2026-04-07