Clinical Trial

Perioperative Oral Decontamination and ImmunoNuTrition (POINT) in Elderly

Study acronym: POINT
Unknown
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Record status
This record was last updated January 28, 2025 (before its estimated August 1, 2025 completion). Its status may not reflect the trial's current state.
Summary
The goal of this multicenter randomized controlled trial is to explore the efficacy of perioperative oral decontamination and immunonutrition supplement to prevent postoperative pulmonary complications in elderly patients(≥65 years) receiving elective non-cardiac operations. Participants will be either given immunonutrition supplement versus routine nutrition advice, and oral chlorhexidine decontamination versus routine oral care randomly. The two interventions will be compared with control groups separately regarding postoperative pulmonary complications and other outcomes.
Protocol Amendment History 1 change
critical Trial status changed: Recruiting → Unknown 2026-08-02
Trial Details
NCT Number NCT05971810
Lead Sponsor Peking Union Medical College Hospital
Collaborators: Fujian Provincial Hospital, The Second Hospital of Hebei Medical University, Shenzhen Nanshan District Shekou People's Hospital, Ningbo No.2 Hospital, Peking University International Hospital, Guizhou Provincial People's Hospital
Conditions Postoperative Complications, Pulmonary Complication
Enrollment 592 participants
Start Date 2023-08-23
Primary Completion 2025-08-01 (estimated)
Study Completion 2025-09-01 (estimated)
Updated on ClinicalTrials.gov 2025-01-28