Supercharged TRAM Evaluation in Cervical Esophagogastroplasty After Esophagectomy

Esophagectomy has high rates of morbidity and mortality, in many cases due to esophagus reconstruction. Anastomotic leakage and fistula are the main esophagectomy complications. Many studies underwent to investigate the cause for anastomotic leakage after esophagectomy, however none of them conclude it is related to surgery or suture technique. However, it seems to be triggered by the ischemia caused after stomach mobilization to esophagus reconstruction, or even tension in the anastomosis. Considering the post esophagectomy with gastroplasty high morbidity and mortality rates, strategies to create a new vascularization source and decrease anastomotic leakage rates is important. In this study researchers will evaluate whether a TRAM flap transfer supercharged is effective on decrease morbidity related to anastomosis ischemia in patients undergoing esophagectomy.

NCT Number	NCT05954702
Lead Sponsor	Instituto do Cancer do Estado de São Paulo
Conditions	Esophagus Cancer, Carcinoma Esophagus
Enrollment	60 participants
Start Date	2023-07-21
Primary Completion	2025-07 (estimated)
Study Completion	2026-10 (estimated)
Updated on ClinicalTrials.gov	2023-10-16