Effect Of Resistive Capactive Electrical Transfer Therapy In Difficult-to-heal Wounds

Difficult-to-heal wounds present imbalances in cytokine production, increases in MMP expression, high levels of apoptosis, and decreases in the proliferation of cells such as fibroblasts and keratinocytes, which are involved in tissue regeneration. CRET therapy (capacitive resistive electrical transfer therapy) has been shown to generate granulation tissue in in vitro assays. In addition, available clinical case reports and preliminary clinical trial results indicate that CRET can promote the regeneration of acute wounds and DHW (difficult-to-heal wounds).

NCT Number	NCT05953935
Lead Sponsor	Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Conditions	Difficult-to-heal Wounds
Enrollment	137 participants
Start Date	2024-01-31
Primary Completion	2024-07-31 (estimated)
Study Completion	2025-06 (estimated)
Updated on ClinicalTrials.gov	2024-09-19