Clinical Trial

Continuation Of a Study to Investigate the Effect of Thoracocentesis on Neural Respiratory Drive in Pleural Effusion

Study acronym: COSINE
Recruiting
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Summary
The aim of this study is to better understand the relationship between pleural effusions and breathlessness in patients with unilateral pleural effusions and breathlessness who require pleural fluid removal for its management.
Trial Details
NCT Number NCT05945043
Lead Sponsor Guy's and St Thomas' NHS Foundation Trust
Conditions Pleural Effusion
Enrollment 124 participants
Start Date 2023-11-15
Primary Completion 2027-06-30 (estimated)
Study Completion 2027-06-30 (estimated)
Updated on ClinicalTrials.gov 2026-06-04