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Virtual Rehabilitation in HCT

StatusCompleted
PhaseNot applicable
Started2023-07-31
View on ClinicalTrials.gov ↗

Amendment history

2026-09-17
notable
Trial completed
Final enrollment: 20 participants (planned 40)
Primary completion confirmed: July 2026 (last estimated August 2027)
2025-09-15
minor
Study Status v3
Re-verified, no change to tracked fields
2024-09-12
minor
Study Status, Oversight, Study Description, Eligibility, Contacts/Locations v2
Eligibility criteria+4 characters
Inclusion Criteria: Recipients between the ages of 8 and 2123 years ≥100 days post allogeneic HCT. Patients 8-14 years old should have a caregiver willing to assist with the implemen [...] exercise as evaluated by the treating physician. Non-English-speaking patients (due to a lack of available interpreters through the telemedicine platform).
Study sitescontacts updated at 1 of 1 site
2023-08-30
notable
Not Yet Recruiting→Recruiting Study Status, Contacts/Locations v1
Trial statusNot Yet Recruiting→Recruiting
Start dateestimated 2023-07→confirmed 2023-07-31
Study sitesdetails revised at 1 of 1 site
2023-07-05
minor
Original filing
Chronic GVHD (cGVHD) is a major cause of illness in patients who undergo hematopoietic transplantation (HCT). GVHD can affect any organ in the body, can require several years of treatment, and can impact the quality of life (QoL). Physical activity and exercise have been shown to enhance fitness and improve QoL in chronic illnesses including GVHD, however, patients often have barriers to attending sessions including distance, risk of infection, and physical therapists' lack of experience with pediatric patients. The team's goal is to assess whether a virtual rehabilitation program in children post-HCT (including children with chronic GVHD) is feasible and whether its implementation will improve physical functioning and QoL. Patients between the ages of 8 and 23 years who are at least one hundred days post-HCT will be eligible for participation. Patients will have an assessment by a pediatric physical therapist at the time of study entry, at the end of the rehabilitation program, and approximately 3 months later. They will be supplied with some exercise equipment (such as dumbbells and resistance bands). Patients will have twice weekly half-hour one-on-one online sessions with the physical therapist for 12 weeks. Patients will be recruited through the bone marrow transplant clinic.
Trial Details
NCT Number NCT05943964
Lead Sponsor Emory University
Collaborators: Incyte Corporation
Conditions Hematopoietic Cell Transplant
Enrollment 20 participants
Start Date 2023-07-31
Primary Completion 2026-07-07 (estimated)
Study Completion 2026-07-07 (estimated)
Updated on ClinicalTrials.gov 2026-09-16